Life in the Bladerunner world reduces down to three questions, according to Ford's voiceover: where do i come from? where am i going? how long have i got?? The blurring between humans and technology means replicants and humans alike want the answers.
So how are humans distinct? "Feelings", or some kind of (subjective) emotionality is even shown to be a commonality. This throws human AND individual identity into question even as it exposes the contrived-ness of "feelings" like love and trust. How do you know who you are when you can't even trust your senses? Showing the "equality" of humans and replicants presents a cutting critique of humanness. What right do they have to retire replicants? but how can they do anything but retire those that pose such an implicit threat as the sum of humans' best attributes?
So how are humans distinct? Their superiority rests in their access to Information: they know or can find out the answers to the replicant's three questions. Male Humans play Father/God to the replicants, grasping power by old-fashioned withholding-of-information. He is simultaneously righteous in his superiority and possibly at some level envious of the knowable-ness of the replicants' "identity" as he constantly confronts his own unknowableness. or defers confronting it by righteously hunting replicants. or seducing them.